Augmenting Endogenous Levels of Retinal Annexin A1 Suppresses Uveitis in Mice
نویسندگان
چکیده
منابع مشابه
Augmenting Endogenous Levels of Retinal Annexin A1 Suppresses Uveitis in Mice
PURPOSE The purpose of this study was to examine the expression of the anti-inflammatory protein Annexin A1 (AnxA1) in mice and human retinae during uveitis and to determine whether local administration of human recombinant AnxA1 (hrAnxA1) can suppress uveitis in mice. METHODS Retinal sections from mice (healthy normal and uveitis) and postmortem human (no history of eye disease (n = 5) and u...
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objective: annexin a1 (anxa1) is suggested to have anti-inflammatory function. however, the precise function of anxa1 has remained unclear. in this study, we therefore examined the potency of anxa1 in regulating reactive oxygen species (ros) production and suppressing pro-inflammatory responses in pc12 cells induced by 1-methyl-4-phenylpyridinium (mpp+). materials and methods: in this experimen...
متن کاملImmunoglobulins in endogenous uveitis.
Examination of 300 patients suffering from endogenous uveitis revealed raised levels of IgG in 24 per cent, IgA in 17 per cent, and IgM in 10 per cent. A raised level of one or more immunoglobulins was found more frequently in anterior uveitis than in the posterior form (44 compared with 24 per cent), in bilateral cases (47 compared with 35 per cent), and in relation to certain general diseases...
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ژورنال
عنوان ژورنال: Translational Vision Science & Technology
سال: 2017
ISSN: 2164-2591
DOI: 10.1167/tvst.6.5.10